The nanofibers can adhere to the wound directly, and the matrix formed by the fibers provides a scaffold that biologically mimics the structure of human tissue.
FREMONT, CA: Conventional dressings, such as gauze bandages, foam dressings, and adhesive pads, must be replaced regularly to protect wounds from infection and check healing progress, which frequently causes additional trauma to the patient and disrupts the recovery process. In addition, wound infections are significant complications that necessitate different treatment, which prolongs hospitalization and recovery time and may result in poor scarring.
Electrospinning technology, which uses electrostatic forces to create a nanofibrous synthetic skin-like matrix, is gaining traction as a potentially excellent alternative for wound dressing. It can be a beneficial solution because certain additives, such as antibacterial, silicon, collagenous, or even cell-based therapies, can be 'interwoven' into the fibers to improve matrix performance and healing.
However, the few electrospun dressing solutions still have some of the common drawbacks of traditional dressings. They are limited in offering a 'one-size-fits-all' solution because they are manufactured on industrial machines and are supplied to hospitals in set templates that must then be cut to size by medical teams and still require adhesives and secondary dressings to secure them to the wound.
The ability to deliver a personalized solution in which the fibers are imprinted directly onto the wound is required. One that can perfectly follow the body's contours, adhering directly to the wound and usually requiring no secondary dressing.
These nanofibrous dressings of the future allow the wound to heal while new skin regenerates beneath. They may also be able to 'piggyback' on other technologies, such as cell-regeneration therapies. This can help to accelerate the healing process, avoid surgical procedures, reduce the need for ongoing pain relief, and reduce emotional trauma. As a result, both physical and mental scars have been reduced.
This isn't some fantastical vision. Portable electrospinning technologies are available and can provide medical providers—surgeons, emergency room doctors, and nurse practitioners – with the required tools. With time, this portability could move wound treatment out of surgical wards and into the hands of emergency medical responders and (eventually) into businesses or homes. Through cutting-edge technologies, we will be able to create personalized wound treatments that meet the needs of medical teams while also significantly improving patient experience and quality of life.