Of hospitalized children who tested positive for SARS-CoV-2, 44 percent developed neurological symptoms, and were more likely to require intensive care than their peers who didn't experience such symptoms.
FREMONT, CA: Headache and altered mental status, often known as acute encephalopathy, were the most prevalent neurological symptoms. These preliminary findings, which were published in Pediatric Neurology, are the first from the paediatric arm of GCS-NeuroCOVID, an international multi-centre partnership aimed at understanding how COVID-19 affects the brain and nervous system.
The SARS-CoV-2 virus can affect cpaediatri patients in a variety of ways. It can cause acute disease, where symptoms appear shortly after an infection, or children may develop an inflammatory condition called MIS-C weeks after clearing the virus. One of the consortium's main concerns was whether neurological symptoms in juvenile patients differed or were comparable depending on which of these two diseases they had. The researchers sought the help of 30 paediatric critical care clinics from around the world to answer this question. A total of 1,278, or 86 percent, of the 1,493 hospitalised children have diagnosed with acute SARS-CoV-2; 215 children, or 14 percent, were diagnosed with MIS-C, or multisystem inflammatory syndrome, which is characterised by fever, inflammation, and organ dysfunction and typically appears several weeks after the virus has been cured.
Headache, acute encephalopathy, and seizures were the most common neurologic manifestations connected to acute COVID-19, while headache, acute encephalopathy, and dizziness were the most common neurologic manifestations linked to MIS-C. Loss of smell, eye impairment, stroke, and psychosis was among the more uncommon symptoms of both illnesses. The study found that children with MIS-C were more likely than those with acute SARS-CoV-2 to have neurological signs and that children with MIS-C were more likely than those with acute sickness to have two or more neurologic manifestations. On a long-term basis, this study intends to create a database that follows neurological signs throughout time, not only for SARS-CoV-2, but for other types of infections as well. Also, some nations have fantastic databases that allow them to readily track and compare children who are hospitalized, but the United States do not possess such a resource.