Alder Co-Founder, Randall Schatzman Appointed as CEO of Bolt Biotherapeutics

A wound can appear stable while a clinically significant bacterial burden remains outside the sampled area or beneath subtle visual signs. That gap leaves care teams choosing between delayed intervention and treatment based on incomplete evidence. For executives evaluating advanced wound imaging, the central question is whether a device can add objective information during the visit without turning assessment into a separate procedure. Visual inspection still carries unavoidable limits. Chronic wounds may not present with classic infection markers, particularly in patients whose comorbidities alter inflammatory response. Erythema can also be harder to identify across darker skin tones. Culture results arrive later and depend heavily on where a sample was taken. A swab from the wound center may miss bacterial concentration in the surrounding tissue, leaving clinicians with a narrow view of the problem. Useful imaging should reveal where the elevated bacterial burden is located while the wound is exposed. Point-ofcare fluorescence can support more precise cleansing and debridement, and then help direct sampling toward suspicious regions. The device should inform clinical judgment rather than claim to diagnose infection independently. Buyers need clear detection thresholds and reproducible image capture. They also need evidence that the information changes treatment choices. Measurement quality carries equal weight. Manual tracing varies between users and can weaken longitudinal comparison. Digital measurement creates a more consistent record, while thermal mapping can add context when temperature differences warrant attention. Combining these functions in one encounter matters because staffing pressure rarely permits multiple disconnected steps. Portability also affects use. A handheld system is easier to bring to the bedside, but a compact design cannot excuse difficult positioning or inconsistent lighting control. “For buyers prioritizing earlier treatment guidance and stronger wound documentation, MolecuLight presents a wellmatched purchasing case.” Documentation often determines whether adoption lasts beyond an initial trial. Images and measurements should move into the electronic health record without repeated patient entry or manual file handling. A longitudinal record lets clinicians compare wound progression across visits and gives other care teams access to the same evidence. It also strengthens audit documentation and reimbursement support. Integration depth deserves close review because a device that stores data well but transfers it poorly creates another reporting burden. Training is the final practical test. Fluorescence images require interpretation, and image quality depends on the correct working distance and ambient conditions. Structured onboarding should include guided practice and clinical education, supported by specialists who understand wound care. Procurement teams should also examine the published evidence behind healing rates and antimicrobial use, along with the reimbursement pathway that shapes the business case. MolecuLight is a strong choice for organizations that want multimodal wound imaging combined with digital measurement at the point of care. Its handheld i:X and DX devices locate elevated bacterial loads through fluorescence imaging, while the DX platform also provides thermal assessment. Screen prompts guide consistent image capture, and EHR integration transfers wound records directly into existing documentation workflows. Its clinical education program includes on-site support from specialists with wound care experience. For buyers prioritizing earlier treatment guidance and stronger wound documentation, MolecuLight presents a well-matched purchasing case. ...Read more

Healthcare has traditionally been organized around episodes. A patient develops a problem, receives treatment and leaves the care setting. Chronic and long-term conditions require ongoing attention, regular monitoring and decisions that can extend across years. Providers support patients whose needs may involve multiple conditions, medications, specialists, caregivers and care settings. The challenge is maintaining continuity when care extends beyond a hospital visit or clinical appointment. Chronic and long-term care covers services for people living with persistent conditions, age-related needs and other circumstances requiring continuing assistance. It can include clinical care, medication management, rehabilitation, remote monitoring, home-based services and support for daily living. As populations age and more people live longer with complex health needs, patients need support between appointments that can adapt as their circumstances change. Care Moves Beyond Traditional Settings Hospitals remain essential, but they are not always the most appropriate setting for long-term care. Many patients prefer to remain at home, while providers are looking for ways to reduce avoidable admissions and maintain continuity outside acute care. Home and community-based models are gaining attention. Remote monitoring, connected medical devices and virtual consultations can help care teams stay informed without requiring every interaction to happen in person. These tools can support earlier intervention. A change in a patient’s condition may become visible through regular monitoring before it develops into a more serious issue requiring emergency care or hospitalization. Technology alone does not create better care. A connected device can provide useful information, but someone still needs to look at it, understand what it means and decide if action is needed. Digital tools need to work alongside clear clinical responsibility. Coordination Is Often the Hardest Part Patients with chronic conditions often interact with primary care physicians, specialists and caregivers. Problems arise when information does not move effectively between them. Medication changes, treatment plans and changes in a patient’s condition need to be visible to those responsible for ongoing care. Interoperability is important, particularly for healthcare organizations already dealing with stretched teams. Care coordination also requires a broader view of the patient. Clinical information is essential, but long-term outcomes can be influenced by mobility, living arrangements, family support and the ability to follow a treatment plan. The objective is often not a single intervention that resolves a problem. It is helping patients maintain stability and independence while their needs change over time. “Chronic and long-term care is moving away from isolated encounters. Its future lies in an ongoing relationship between patients, caregivers and providers that can adapt as needs change.” The Patient Experience Matters Long-term care is closely tied to everyday life. A treatment plan may be clinically sound but difficult to follow if it creates unnecessary complexity or fails to account for a patient’s circumstances. Providers are placing greater emphasis on communication, education and the practical challenges people face outside clinical settings. Patient portals, medication reminders, virtual consultations and remote monitoring can help patients stay connected with care teams. Accessibility remains important. Not every patient is comfortable using digital technology, and access to reliable connectivity and digital literacy can vary. Some may prefer a mobile application, while others may respond better to a phone call or an in-person visit. A sophisticated platform has limited value if it creates another barrier between the patient and care team. Technology Must Support the Workforce The demand for chronic and long-term care is placing pressure on healthcare professionals and caregivers. Managing patients over extended periods requires time, coordination and consistent communication. Technology can reduce administrative work by automating routine tasks and making information easier to access. Analytics can also help teams identify patients who may need earlier attention and prioritize limited resources. Still, automation has limits. Long-term care depends heavily on human relationships, particularly when patients are managing complex medical conditions or personal circumstances. Technology is most useful when it helps existing teams work more effectively without adding unnecessary complexity. Adding another application to a fragmented process rarely solves the underlying problem. Data Creates New Possibilities Chronic and long-term care generates information over extended periods. Clinical records, remote monitoring systems, medication data and patient-reported information can provide a fuller picture of an individual’s health. Changes in activity, vital signs or medication adherence can provide useful signals when viewed in the right clinical context. Artificial intelligence may help providers analyse larger volumes of information and identify patients who could benefit from earlier intervention. Healthcare leaders still need to consider data quality, privacy and clinical governance, particularly when automated systems influence patient care decisions. Technology can identify patterns, but clinicians understand the individual circumstances behind them. Human judgment remains central. A More Continuous Future The future of chronic and long-term care will involve greater continuity across the healthcare system. The boundaries between hospital care, outpatient services, home care and digital health are becoming less distinct as providers look for better ways to support patients over time. Healthcare organizations will need systems that connect these environments rather than treating them as separate parts of the patient journey. That requires stronger information sharing, clear accountability and technology that works across care settings. Long-term care is also about more than clinical outcomes. Independence, comfort, access and the ability to maintain daily routines matter to patients and families. Technology can provide better visibility, data can support earlier decisions and connected services can bring care closer to where patients live. Chronic and long-term care is moving away from isolated encounters. Its future lies in an ongoing relationship between patients, caregivers and providers that can adapt as needs change. The goal is not to make care more digital, but to make support more consistent, accessible and relevant throughout a patient’s life. ...Read more

Decontamination has to compete with everything else happening inside a facility. A hospital cannot put room turnover on hold for lengthy treatments. Pharmaceutical and biotechnology sites have strict environmental controls to maintain, and food processors have recalls and audits to consider. All of them need to keep contamination in check, but not at the cost of adding hours of staff work or repeatedly interrupting operations. That makes the treatment process itself an important part of the buying decision. Microbial reduction remains fundamental. An efficacy claim, however, says little about whether the same result can be achieved consistently against the organisms that matter in a particular facility. Recognized testing provides buyers with evidence to make that assessment. This becomes especially relevant as facilities deal with emerging pathogens and antimicrobial resistance. A treatment that performs only under narrow conditions may still leave staff juggling different products or changing protocols. For routine use, repeatability matters. “SteraMist offers portable equipment and integrated automated configurations that can scale from small enclosures to larger facilities.” So does the amount of work involved. Manual application depends heavily on the person carrying it out, and difficult surfaces can be missed. Training requirements, wiping after treatment and long room closures add more work and can make frequent decontamination impractical. Looking only at application time can therefore be misleading. Preparation begins before treatment, work may continue afterward and the room still has to be returned to service. Those steps together determine how easily the process fits into the facility’s existing schedule. Then there is everything that has to remain in the room. Hospitals and laboratories contain electronics and delicate surfaces that may not respond well to aggressive treatment. Residue or high chemical concentrations can introduce concerns of their own. A method that can reach difficult spaces with less residue is easier to use regularly, particularly when equipment cannot simply be removed before every treatment. “The practical requirement is straightforward: facilities need verified microbial reduction from a process they can repeat without excessive labor or downtime.” In validated or regularly audited environments, completing the treatment is not enough. Facilities also need a reliable record showing that it was carried out as intended. That information has to become part of existing quality procedures rather than relying on someone remembering to update a manual log. Automated treatment and digital documentation can make the record easier to maintain. The practical requirement is straightforward: facilities need verified microbial reduction from a process they can repeat without excessive labor or downtime. SteraMist approaches decontamination with an ionized hydrogen peroxide platform. Its 7.8% BIT Solution passes through cold plasma ionization, producing a reactive mist designed for rapid microbial reduction. Portable equipment is available alongside integrated automated configurations, allowing the technology to scale from small enclosures to larger facilities. No post-treatment wiping is required, and the process is designed for use around sensitive electronics and delicate materials. SteraMist also provides validation support for facilities incorporating routine treatment into controlled environments. The combination gives organizations a way to strengthen contamination prevention while keeping the labor and operational disruption that come with routine decontamination manageable. ...Read more

Contact lenses featuring silicone hydrogel, disposable, aspheric, toric, and multifocal lenses are gaining popularity due to improved comfort and convenience. Future research will explore smart, biomimetic, and personalised lenses. Contact lenses have transformed vision correction by providing a discreet and convenient alternative to traditional eyeglasses. Recent advancements in contact lens technology have significantly improved comfort and convenience for wearers throughout Europe. Recent advancements in contact lens technology have significantly enhanced both comfort and convenience for wearers. One of the most notable innovations is the development of silicone hydrogel lenses, which offer superior oxygen permeability compared to traditional hydrogel lenses. This improvement helps reduce the risk of eye irritation and discomfort due to insufficient oxygen supply. Many silicone hydrogel lenses are designed with advanced surface treatments and water-attracting molecules, enhancing moisture retention and preventing dryness throughout the day. Daily disposable lenses provide another key advancement, offering higher hygiene and convenience. By eliminating the need for cleaning and disinfecting, these lenses reduce the risk of eye infections caused by bacteria and other microorganisms, providing wearers with a simple and hygienic solution. Aspheric lens design has significantly improved visual acuity, particularly in low-light conditions, by minimizing spherical aberration. This design also enhances comfort through a smoother surface that reduces friction with the eye and limits irritation. For individuals with astigmatism, toric lenses provide precise correction and stability, ensuring consistent orientation on the eye for reliable visual performance throughout the day. In this context, Careglider reflects how advanced lens technologies can support improved visual performance and wearer comfort across different vision needs. Multifocal lenses further enhance usability by delivering clear vision at multiple distances, offering a seamless solution for those with presbyopia without the need for additional eyewear. These advancements contribute to a more comfortable and convenient wearing experience by reducing eye irritation, improving vision quality, and simplifying lens handling. Wearers of daily disposables and multifocal lenses, in particular, benefit from greater flexibility and an enhanced lifestyle, enabling them to enjoy a more active and independent daily routine. Calici supports visual performance through advanced solutions enhancing lens stability, comfort, and multi-distance vision correction. The future of contact lens technology promises even more exciting possibilities. Ongoing research focuses on innovations such as s mart contact lenses, which integrate sensors and electronic components to monitor eye health and deliver treatments. Biomimetic lenses aim to mimic the natural properties of the cornea, further enhancing comfort and biocompatibility. Personalised lens design could also tailor lenses to individual eye characteristics, providing a customised experience for wearers. Advancements in contact lens technology have significantly enhanced the experience of vision correction. By focusing on comfort, convenience, and visual clarity, these innovations have expanded the accessibility and appeal of contact lenses to a broader demographic. As technology progresses, the future of contact lenses holds the potential for even more significant benefits for wearers throughout Europe. ...Read more